Clomid 25 mg Sanofi

Overview

Clomid is a popular brand name and nickname for generic clomiphene citrate.

How does Clomid work?

Clomid blocks the hormone estrogen from interacting with the pituitary gland. When estrogen interacts with the pituitary gland, less luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are produced.

This leads to a decrease in testosterone and therefore decreased sperm production. Because Clomid blocks estrogen’s interaction with the pituitary gland, there’s an increase in LH, FSH, and testosterone in the body.

Optimal dosing in males hasn’t been established. The dose given can range from 12.5 to 400 milligrams (mg) per day.

A recent review recommends a starting dosage of 25 mg three days per week and then slowly titrating — or adjusting the dosage — until the dose is 50 mg per day as needed.

High doses of Clomid can actually have a negative effect on sperm count and motility. Always work with your healthcare provider to ensure proper dosage.

When is Clomid prescribed?

Clomid is prescribed off-label for male infertility, particularly where low testosterone levels are observed.

What are the side effects of this medication?
There are few controlled studies of Clomid use in males. However, possible side effects due to induced hormonal changes include:

• tenderness of the pectoral muscle
• irritability
• acne
• acceleration of prostate cancer growth (if cancer is already present)
• changes in vision that are caused by a swelling of the pituitary gland (rare)